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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS7
All Species:
10.91
Human Site:
S238
Identified Species:
20
UniProt:
O14512
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14512
NP_055413.1
581
62969
S238
D
G
T
G
K
R
P
S
G
E
L
A
A
S
A
Chimpanzee
Pan troglodytes
XP_512211
535
59559
E181
D
F
H
D
L
Q
S
E
T
T
C
Q
E
Q
A
Rhesus Macaque
Macaca mulatta
XP_001082440
360
39867
A48
L
T
D
M
G
G
S
A
G
R
E
L
D
A
G
Dog
Lupus familis
XP_548159
411
45633
T98
A
G
R
K
P
R
L
T
R
T
Q
S
A
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHQ2
579
62765
S236
D
G
T
G
K
R
P
S
G
D
L
A
A
S
A
Rat
Rattus norvegicus
XP_001081372
564
60962
S221
D
G
T
G
K
R
P
S
G
D
L
A
A
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506079
518
56852
F175
P
N
G
V
R
K
D
F
R
E
L
Q
P
D
G
Chicken
Gallus gallus
XP_423895
264
29931
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684929
733
79803
K390
K
V
P
G
K
S
R
K
G
S
L
K
I
R
L
Tiger Blowfish
Takifugu rubipres
NP_001116335
565
61771
V221
L
L
D
K
R
P
S
V
T
Y
S
V
S
S
A
Fruit Fly
Dros. melanogaster
NP_523390
1016
110741
K644
S
A
G
G
G
G
G
K
Y
L
S
K
Q
N
K
Honey Bee
Apis mellifera
XP_397211
804
90105
I411
S
D
S
S
E
N
K
I
K
R
D
N
K
A
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792866
847
94386
M229
K
L
S
V
G
G
L
M
G
D
E
S
E
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
43
69.5
N.A.
97.4
95.1
N.A.
24.1
42.6
N.A.
38.2
52.3
22
24.8
N.A.
27.8
Protein Similarity:
100
36.8
49.5
69.7
N.A.
98.1
95.8
N.A.
34.4
43.7
N.A.
48.2
62.4
32.1
39.2
N.A.
39
P-Site Identity:
100
13.3
6.6
20
N.A.
93.3
93.3
N.A.
13.3
0
N.A.
26.6
13.3
6.6
0
N.A.
13.3
P-Site Similarity:
100
20
20
40
N.A.
100
100
N.A.
26.6
0
N.A.
26.6
26.6
13.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
8
0
0
0
24
31
16
39
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
31
8
16
8
0
0
8
0
0
24
8
0
8
8
0
% D
% Glu:
0
0
0
0
8
0
0
8
0
16
16
0
16
0
8
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
0
31
16
39
24
24
8
0
47
0
0
0
0
0
16
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
16
0
0
16
31
8
8
16
8
0
0
16
8
0
8
% K
% Leu:
16
16
0
0
8
0
16
0
0
8
39
8
0
0
8
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
0
0
8
0
8
0
% N
% Pro:
8
0
8
0
8
8
24
0
0
0
0
0
8
0
8
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
8
16
8
8
0
% Q
% Arg:
0
0
8
0
16
31
8
0
16
16
0
0
0
8
0
% R
% Ser:
16
0
16
8
0
8
24
24
0
8
16
16
8
39
8
% S
% Thr:
0
8
24
0
0
0
0
8
16
16
0
0
0
0
0
% T
% Val:
0
8
0
16
0
0
0
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _